Workshops

  Wednesday, March 24, 9:00 am-5:00 pm

ECDYSONE
Room: Hoover Room
Organizers: Laurie H. von Kalm, University of Central Florida, Orlando; and Lucy Cherbas, Indiana University, Bloomington
 
Summary: The workshop will focus on the role of ecdysteroids in development. Topics to be covered include molecular analysis of transcriptional regulators in the ecdysone response, interactions between the ecdysone and patterning gene hierarchies, tissue-specific responses to ecdysone, regulation of ecdysteroid biosynthesis, and technical advances of interest to researchers in the field.

  Friday, March 26, 2:00 pm-4:00 pm

GENETICS OF NON-DROSOPHILID INSECTS: EMERGING MODELS
Room: Maryland A
Organizers: Jack Werren, University of Rochester, NY; and Claude Desplan, New York University, NY
 
Summary: The goal of this workshop is to present advances in genetic studies of insects other than Drosophila. The workshop will focus on several emerging models for insect genetics, including Tribolium, the honey bee, parasitic wasps Nasonia and Copidosoma, and the pea aphid. Topics include comparative genomics, evo-devo and behavioral genetics.
 
Speakers:
Hugh Robertson   University of Illinois, Urbana
Yehuda Ben-Shahar   University of Iowa, Iowa City
Miodrag Grbic   University of Western Ontario, London, Canada
Leo Beukeboom   University of Gröningen, Germany
John Werren   University of Rochester, NY
Dave Stern   Princeton University, NJ
Yoshi Tomoyasu   Kansas State University, Manhattan
Joel Savard   University of Cologne, Germany
 
FUNCTIONAL GENOMICS OF MITOCHONDRIA
Room: Maryland B
Organizer: David Rand, Brown University, Providence, RI
 
Summary: Mitochondrial genetics is well developed in other model systems such as yeast, but genetic analyses of mitochondria represent a sporadic and dispersed part of the Drosophila literature. The main goal of the workshop is to consolidate different aspects of mitochondrial research. The functional genomics of mitochondria includes anything functional, genetic or genomic about mitochondrial biology. Researchers from labs focusing on mtDNA replication, oogenesis, aging, population genetics and comparative genomics will present their findings. We hope to unite biochemical, cellular, population genetic and evolutionary lines of inquiry in one informal session.
 
Speakers:
David Rand   Brown University, Providence, RI
Laurie S. Kaguni   Michigan State University, East Lansing
Bill Ballard   University of Iowa, Iowa City
Allan Spradling   Carnegie Institute of Washington, Baltimore, MD
Rachel Cox   Carnegie Institute of Washington, Baltimore, MD
Avis James   University of Iowa, Iowa City
Bill Ballard   University of Iowa, Iowa City
John Phillips   University of Guelph, Ontario, Canada
Stephen Helfand   University of Connecticut, Farmington
 
OLFACTORY LEARNING AND MEMORY
Room: Maryland C
Organizers: Scott Waddell, University of Massachusetts Medical School, Worcester; and Efthimios M. C. Skoulakis, Institute of Molecular Biology and Genetics, Vari, Greece
 
Summary: The goal of this workshop is to increase the exposure of the field of learning and memory amongst the greater fly community. We particularly wish to encourage students already in the fly community to become interested in this stimulating area of research. Secondly, we wish to use this workshop as an annual event that will bring researchers in the field together to discuss current work and foster collaboration and communication.

  Saturday, March 27, 7:00 pm-9:00 pm

RNA BIOLOGY
Room: Maryland B
Organizer: Susan R. Haynes, Uniformed Services University of the Health Sciences, Bethesda, MD
 
Summary: The goal of this workshop is to bring together Drosophilists who work on all aspects of RNA biology for informal discussions of common interests. Topics include RNA-protein interactions, the regulation and mechanisms of RNA splicing, polyadenylation, localization, stability, and export, and micro-RNAs and other non-coding RNAs.
 
CHROMATIN STRUCTURE AND THE CELL CYCLE
Room: Maryland A
Organizer: John Manak, Stanford University School of Medicine, CA
 
Summary: The goal of the workshop is to bring together Drosophila researchers who work on genes involved in regulating chromatin structure. An emphasis will be placed on genes that are involved in processes important for cell cycle progression. Topics will include heterochromatin, centromeres, histones and histone variants, histone and chromatin modifications, chromosome condensation, chromatid cohesion, and DNA replication.
 
STEM CELLS
Room: Maryland C
Organizers: Sumana Datta, Texas A&M University, College Station; and Haifin Lin, Duke University Medical School, Durham, NC
 
Summary: This workshop will focus on cutting edge discoveries in the control of stem cell division, maintenance of stem cell identity, analyses of stem cell lineage and mechanisms of determining the identity of stem cell progeny. We are beginning to see common players as well as common issues in different stem cell systems. The organizers hope to bring together researchers in the disparate areas of oogenesis, neural development and cell cycle, and to encourage groups to explore new stem cell systems.
 
DROSOPHILA RESEARCH AND PEDAGOGY AT PRIMARILY UNDERGRADUATE INSTITUTIONS
Room: Virginia B
Organizers: Karen Hales, Davidson College, NC; Cris Cheney, Pomona College, CA; Bev Clendening, Hofstra University, Hempstead, NY; and Elaine Reynolds, Lafayette College, Easton, PA
 
Summary: The workshop goals are fourfold: 1) to provide a forum in which undergraduate students give oral presentations on their research; 2) to bring together faculty from primarily undergraduate institutions (PUIs) for discussions and support on professional issues that differ from those at large institutions; 3) to share ideas for using Drosophila as teaching tools in the classroom and laboratory; and 4) to connect people interested in PUI jobs with people already in such positions.

  Saturday, March 27, 9:30 pm-11:30 pm

MECHANISMS OF TRANSLATION
Room: Maryland B
Organizer: Rolando V. Rivera Pomar, Max Planck Institute for Biophysical Chemistry, Göttingen, Germany
 
Summary: The workshop intends to present and discuss advances in the molecular biology of protein synthesis using Drosophila as model organism. Translational control during Drosophila early embryogenesis is well studied, however the mechanisms underlying the control and the role of translation factors is still not fully understood. Several laboratories that study basic mechanisms of translation in eukaryotes have just discovered that Drosophila is an excellent model to study the function of translation factors and the basic mechanism of protein synthesis, as well as answer basic questions on the relationship between protein synthesis, cell proliferation, cell growth and cell death.
 
CELL CYCLE CHECKPOINTS
Room: Maryland A
Organizers: Tin Tin Su, University of Colorado, Boulder; and Claudio Sunkel, Universidade do Porto, Portugal
 
Summary: The goal of the workshop is to discuss the regulation of the cell cycle by DNA damage, DNA replication and spindle checkpoints.
 
IMMUNITY, PATHOGENESIS AND HEMATOPOIESIS
Room: Maryland C
Organizer: Catherine Brennan, Sloan-Kettering Institute, New York, NY
 
Summary: Presentations in this workshop will focus on the effector cell types and molecules as well as on the regulatory mechanisms that govern humoral and cellular immune responses in Drosophila. Topics relating to host pathogen interactions and Drosophila hematopoiesis will also be discussed.
 
EXTRACELLULAR MATRIX INTERACTIONS AND SIGNALING
Room: Virginia A
Organizers: Rolf Bodmer, The Burnham Institute, La Jolla, CA; Hannele Ruohola-Baker and Kathie Jordan, University of Washington, Seattle
 
Summary: Until recently, the extracellular matrix (ECM) was thought to act only as a stabilizing scaffold. Recent findings, discussed in this workshop will bring through the point that ECM has a more active, regulatory role in processes such as cellular migration, polarity, morphogenesis, signaling and development.
 
Presenters:
1. Matt Gibson (Perrimon lab): Thickvein-mutant cells extruded from the developing wing epithelium: ECM effects?
2. Ethan Bier: Diffusion of sog and dpp in patterning the embryonic ectoderm
3. Chino Kumagai-Cresse
(Fessler lab):
Nidogen in Drosophila Basement Membranes and Sense Organs
4. Uri Nudel: The drosophila homologue of the dystrophin gene: structure, products, evolution, and expression
5. Cathy Torgler
(Brown lab):
Tensin/blistery stabilises integrin adhesive contacts in Drosophila
6. Karl Johnson
(Van Vactor Lab):
Heparan Sulfate Proteoglycans Regulate Axon Guidance at the Midline Choice Point
7. Andrea Page-McCaw: Matrix Metalloproteinases in Drosphila Development
8. Patrick Devine
(Krasnow lab):
Function of a Drosophila matrix metalloproteinase in tracheal outgrowth and pathfinding
9. Li Qian
(Bodmer lab):
Control of cardiac cell polarity and morphogenesis
10. Petros Ligoxygakis: Serpin regulation of dorsal-ventral axis formation in the Drosophila embryo

GRAVITY AND THE FLY
Room: Virginia B
Organizers: Kathleen M. Beckingham, Rice University, Houston, TX; and Sharmila Battacharya, NASA Ames Research Center, Moffett Field, CA

Summary: Drosophila is emerging as the model organism of choice for studies of gravitational effects in a complex eukaryote. Ongoing work to determine the effects of gravity on fly behavior and gene expression will be discussed, along with efforts to identify the genetic determinants for gravity perception and responsiveness.

Introduction - Kate Beckingham

Gravity Research, Funding and NASA – Sharmila Bhattacharya

  1. Talks
     
    1. Effects of spaceflight on nervous system development
      Presenter: Haig Keshishian
      Keshishian, H., Yoon, K.S, Cole, J.S., Osterwalder, T., Leiserson, W.M
      Molecular, Cellular, and Developmental Biology Dept., Yale University, New Haven, CT
       
    2. Drosophila mutants defective in gravitaxis
      Presenter: Kate Beckingham
      Beckingham, K.1, Texada, M., Munjaal1, R., Armstrong2, J. D., and Simonette1, R.
      1 Dept. Biochemistry and Cell Biology, Rice University and 2 School of Informatics, Institute for Adaptive and Neural Computation, University of Edinburgh, UK
       
    3. Genotype-expression-phenotype correlations in Drosophila gravitaxis.
      Presenter: Dan Toma
      Toma, D.P.,1 White, K.P.,2 and Greenspan, R.J.1
      1
      The Neurosciences Institute, San Diego, CA 92121, and 2Department of Genetics, School of Medicine, Yale University, 06520
       
    4. Effects of increased gravity on behavior of adult Drosophila
      Presenter: Sharmila Bhattacharya
      Bhattacharya, S., Sanchez, M.E., Fahlen, T.F., and Stowers, R.S.
      NASA Ames Research Center, Moffett Field, CA 94035.
       
    5. A multi-generation mutation accumulation experiment for the International Space Station.
      Presenter: James Thompson
      Thompson, J. N1., jr., and R.C. Woodruff, R.C.2.
      1Dept of Zoology, University of Oklahoma, Norman, OK, and 2Dept Biological Sciences, Bowling Green State University, Bowling Green, OH.
       
  2. Round Table Discussion Presentations
     
    1. Infection and Gravity
      Presenter: Kimbrell, Deborah
      Kimbrell, D.
      Dept Biology, U. C. Davis, Davis CA
       
    2. Past, present and future of European Drosophila Research in Microgravity
      Presenter: Roberto Marco
      Marco, R.1, Herranz, R1., Martin, E.2, and Horn, E3.
      1 Department of Biochemistry & Instituto "Alberto Sols" UAM-CSIC, and Universidad Autónoma de Madrid, Spain. 2 Instituto de Biologia Molecular de Barcelona, and 3 Department of Neurophysiology, University of ULM, Germany.
       
    3. Natural variation in geotaxis: the ups and downs of Drosophila
      Presenter: Macarena Busto
      Busto,1,M., Riedl1, C.A.L., MacKay, T.F.C.,2 and Sokolowski1, M.B.
      1 Biology Dept, University of Toronto at Mississauga, Mississauga, Ontario, Canada and 2 Genetics Dept, North Carolina State University, Raleigh, NC, USA